The CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 diabetes mellitus in the Portuguese population.

نویسندگان

  • M C Lemos
  • E Coutinho
  • L Gomes
  • M Bastos
  • A Fagulha
  • L Barros
  • F Carrilho
  • E Geraldes
  • F J Regateiro
  • M Carvalheiro
چکیده

CTLA4 genetic polymorphisms have been associated with type 1 diabetes. We genotyped 207 patients and 249 controls for the most frequently investigated polymorphism of the CTLA4 gene (+49A/G (rs231775)). No significant differences were observed, suggesting that this polymorphism is not strongly associated with type 1 diabetes in the Portuguese population.

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عنوان ژورنال:
  • International journal of immunogenetics

دوره 36 3  شماره 

صفحات  -

تاریخ انتشار 2009